BDBM316288 US10294218, Example 116::US9617225, Example 116::[6-(2-Methoxy-phenyl)-pyrimidin-4-yl]-[4-methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-phenyl]-amine

SMILES: COc1ccccc1-c1cc(Nc2ccc(OC)c(c2)C2=CCNCC2)ncn1

InChI Key: InChIKey=YUVIMYFPLYEJEI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 9 (CDK9) (Homo sapiens (Human))	BDBM316288 (US10294218, Example 116 | US9617225, Example 116 |...) Show SMILES COc1ccccc1-c1cc(Nc2ccc(OC)c(c2)C2=CCNCC2)ncn1 |t:22| Show InChI InChI=1S/C23H24N4O2/c1-28-21-6-4-3-5-18(21)20-14-23(26-15-25-20)27-17-7-8-22(29-2)19(13-17)16-9-11-24-12-10-16/h3-9,13-15,24H,10-12H2,1-2H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				Bioorg Med Chem Lett 18: 1022-6 (2008) BindingDB Entry DOI: 10.7270/Q2RB76X4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM316288 (US10294218, Example 116 | US9617225, Example 116 |...) Show SMILES COc1ccccc1-c1cc(Nc2ccc(OC)c(c2)C2=CCNCC2)ncn1 |t:22| Show InChI InChI=1S/C23H24N4O2/c1-28-21-6-4-3-5-18(21)20-14-23(26-15-25-20)27-17-7-8-22(29-2)19(13-17)16-9-11-24-12-10-16/h3-9,13-15,24H,10-12H2,1-2H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
VIROSTATICS SRL US Patent					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				US Patent US9617225 (2017) BindingDB Entry DOI: 10.7270/Q29W0HK6
					More data for this Ligand-Target Pair