BDBM316373 US9617239, BRITE-354969

SMILES: CCN(CCNS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1)c1cccc(C)c1

InChI Key: InChIKey=NOWBKSDJSUZCIL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human))	BDBM316373 (US9617239, BRITE-354969) Show SMILES CCN(CCNS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1)c1cccc(C)c1 Show InChI InChI=1S/C25H32N4O3S2/c1-3-28(21-7-4-6-20(2)18-21)17-14-27-34(30,31)25-11-10-24(33-25)32-23-9-5-8-22(19-23)29-15-12-26-13-16-29/h4-11,18-19,26-27H,3,12-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair