BDBM316375 US9617239, BRITE-355006

SMILES: Cc1ccc(CNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)c(C)c1

InChI Key: InChIKey=ATPSKUXWKBYWSN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human))	BDBM316375 (US9617239, BRITE-355006) Show SMILES Cc1ccc(CNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)c(C)c1 Show InChI InChI=1S/C23H27N3O3S2/c1-17-6-7-19(18(2)14-17)16-25-31(27,28)23-9-8-22(30-23)29-21-5-3-4-20(15-21)26-12-10-24-11-13-26/h3-9,14-15,24-25H,10-13,16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair