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SMILES: FC(F)(F)c1cccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1

InChI Key: InChIKey=MWOAJDCTLPMDGA-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316383   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-glucuronidase


(Homo sapiens (Human))		BDBM316383
PNG
(US9617239, BRITE-354873)
Show SMILES FC(F)(F)c1cccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1
Show InChI InChI=1S/C22H21ClF3N3O3S2/c23-19-13-20(34(30,31)28-14-15-3-1-4-16(11-15)22(24,25)26)33-21(19)32-18-6-2-5-17(12-18)29-9-7-27-8-10-29/h1-6,11-13,27-28H,7-10,14H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 290n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...

US Patent US9617239 (2017)


BindingDB Entry DOI: 10.7270/Q22B913V
More data for this
Ligand-Target Pair