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SMILES: COc1ccc(NC(=O)CCNC2=NC3C(C=NN3C3CCCC3)C(=O)N2)cc1

InChI Key: InChIKey=QCKQWVQYQUNYIV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317143   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A


(Homo sapiens (Human))		BDBM317143
PNG
(US9617269, Compound WYQ-92)
Show SMILES COc1ccc(NC(=O)CCNC2=NC3C(C=NN3C3CCCC3)C(=O)N2)cc1 |c:16,t:12|
Show InChI InChI=1S/C20H26N6O3/c1-29-15-8-6-13(7-9-15)23-17(27)10-11-21-20-24-18-16(19(28)25-20)12-22-26(18)14-4-2-3-5-14/h6-9,12,14,16,18H,2-5,10-11H2,1H3,(H,23,27)(H2,21,24,25,28)
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US Patent
n/an/a 6n/an/an/an/an/an/a



Sun Yat-Sen University; University of North Carolina at Chapel Hill

US Patent


Assay Description
Inhibition activities of all the N-substituted pyrazolo [3,4-d] pyrimidine ketone compounds according to the present invention to the phosphodiestera...

US Patent US9617269 (2017)


BindingDB Entry DOI: 10.7270/Q2RX9F4B
More data for this
Ligand-Target Pair