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BDBM31735 (7Z)-3-bromanyl-7-(furan-2-ylmethylidene)-[1,3]thiazolo[4,5]imidazo[1,2-b]pyridin-8-one::(7Z)-3-bromo-7-(2-furanylmethylidene)-8-thiazolo[4,5]imidazo[1,2-b]pyridinone::(7Z)-3-bromo-7-(2-furfurylidene)thiazolo[4,5]imidazo[1,2-b]pyridin-8-one::(7Z)-3-bromo-7-(furan-2-ylmethylidene)-[1,3]thiazolo[4,5]imidazo[1,2-b]pyridin-8-one::MLS-0091940.0001::cid_6456506

SMILES: Brc1cnc2c(c1)nc1s\c(=C/c3ccco3)c(=O)n21

InChI Key: InChIKey=OJWCRZGASOCMRF-YHYXMXQVSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 31735   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MKP-3


(Rattus norvegicus)
BDBM31735
PNG
((7Z)-3-bromanyl-7-(furan-2-ylmethylidene)-[1,3]thi...)
Show SMILES Brc1cnc2c(c1)nc1s\c(=C/c3ccco3)c(=O)n21
Show InChI InChI=1S/C13H6BrN3O2S/c14-7-4-9-11(15-6-7)17-12(18)10(20-13(17)16-9)5-8-2-1-3-19-8/h1-6H/b10-5-
PDB
MMDB

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PCBioAssay
n/an/a 5.60E+3n/an/an/an/a7.023



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: NIH...


Citation and Details
More data for this
Ligand-Target Pair
MKP-3


(Rattus norvegicus)
BDBM31735
PNG
((7Z)-3-bromanyl-7-(furan-2-ylmethylidene)-[1,3]thi...)
Show SMILES Brc1cnc2c(c1)nc1s\c(=C/c3ccco3)c(=O)n21
Show InChI InChI=1S/C13H6BrN3O2S/c14-7-4-9-11(15-6-7)17-12(18)10(20-13(17)16-9)5-8-2-1-3-19-8/h1-6H/b10-5-
PDB
MMDB

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Article
PCBioAssay
n/an/a 4.40E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver


(Homo sapiens)
BDBM31735
PNG
((7Z)-3-bromanyl-7-(furan-2-ylmethylidene)-[1,3]thi...)
Show SMILES Brc1cnc2c(c1)nc1s\c(=C/c3ccco3)c(=O)n21
Show InChI InChI=1S/C13H6BrN3O2S/c14-7-4-9-11(15-6-7)17-12(18)10(20-13(17)16-9)5-8-2-1-3-19-8/h1-6H/b10-5-
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n/an/a 2.78E+4n/an/an/an/an/an/a



Sanford-Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


Citation and Details
More data for this
Ligand-Target Pair
Dual specificity protein phosphatase (VHR)


(Homo sapiens (human))
BDBM31735
PNG
((7Z)-3-bromanyl-7-(furan-2-ylmethylidene)-[1,3]thi...)
Show SMILES Brc1cnc2c(c1)nc1s\c(=C/c3ccco3)c(=O)n21
Show InChI InChI=1S/C13H6BrN3O2S/c14-7-4-9-11(15-6-7)17-12(18)10(20-13(17)16-9)5-8-2-1-3-19-8/h1-6H/b10-5-
PDB
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n/an/a 345n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


Citation and Details
More data for this
Ligand-Target Pair
Dual specificity protein phosphatase (VHR)


(Homo sapiens (human))
BDBM31735
PNG
((7Z)-3-bromanyl-7-(furan-2-ylmethylidene)-[1,3]thi...)
Show SMILES Brc1cnc2c(c1)nc1s\c(=C/c3ccco3)c(=O)n21
Show InChI InChI=1S/C13H6BrN3O2S/c14-7-4-9-11(15-6-7)17-12(18)10(20-13(17)16-9)5-8-2-1-3-19-8/h1-6H/b10-5-
PDB
MMDB

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n/an/a 1.23E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


Citation and Details
More data for this
Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP)


(Homo sapiens (Human))
BDBM31735
PNG
((7Z)-3-bromanyl-7-(furan-2-ylmethylidene)-[1,3]thi...)
Show SMILES Brc1cnc2c(c1)nc1s\c(=C/c3ccco3)c(=O)n21
Show InChI InChI=1S/C13H6BrN3O2S/c14-7-4-9-11(15-6-7)17-12(18)10(20-13(17)16-9)5-8-2-1-3-19-8/h1-6H/b10-5-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

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PCBioAssay
n/an/a 127n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


Citation and Details
More data for this
Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP)


(Homo sapiens (Human))
BDBM31735
PNG
((7Z)-3-bromanyl-7-(furan-2-ylmethylidene)-[1,3]thi...)
Show SMILES Brc1cnc2c(c1)nc1s\c(=C/c3ccco3)c(=O)n21
Show InChI InChI=1S/C13H6BrN3O2S/c14-7-4-9-11(15-6-7)17-12(18)10(20-13(17)16-9)5-8-2-1-3-19-8/h1-6H/b10-5-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 949n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


Citation and Details
More data for this
Ligand-Target Pair