null

SMILES: CNC(=O)c1ccc(Nc2nc(NC3CCCC3)c3c(c[nH]c3n2)-c2ccc(O)cc2)c(OC)c1

InChI Key: InChIKey=SLKJEEPATPIULR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase CLK2 (Homo sapiens (Human))	BDBM317458 (4-(4-(cyclopentylamino)-5-(4- hydroxyphenyl)-7H-py...) Show SMILES CNC(=O)c1ccc(Nc2nc(NC3CCCC3)c3c(c[nH]c3n2)-c2ccc(O)cc2)c(OC)c1 Show InChI InChI=1S/C26H28N6O3/c1-27-25(34)16-9-12-20(21(13-16)35-2)30-26-31-23-22(24(32-26)29-17-5-3-4-6-17)19(14-28-23)15-7-10-18(33)11-8-15/h7-14,17,33H,3-6H2,1-2H3,(H,27,34)(H3,28,29,30,31,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, LLC US Patent					Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...				US Patent US9623028 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34R8
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM317458 (4-(4-(cyclopentylamino)-5-(4- hydroxyphenyl)-7H-py...) Show SMILES CNC(=O)c1ccc(Nc2nc(NC3CCCC3)c3c(c[nH]c3n2)-c2ccc(O)cc2)c(OC)c1 Show InChI InChI=1S/C26H28N6O3/c1-27-25(34)16-9-12-20(21(13-16)35-2)30-26-31-23-22(24(32-26)29-17-5-3-4-6-17)19(14-28-23)15-7-10-18(33)11-8-15/h7-14,17,33H,3-6H2,1-2H3,(H,27,34)(H3,28,29,30,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, LLC US Patent					Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...				US Patent US9623028 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34R8
					More data for this Ligand-Target Pair