null

SMILES: CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3[C@H](C(C)C)N(Cc3c2)c2nccc(n2)C(F)(F)F)cc1

InChI Key: InChIKey=MSDSXVNQDHJLCU-QFIPXVFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM317853 (S-N-(4-(ethylsulfonyl)benzyl)-7-isopropyl-6-(4-(tr...) Show SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3[C@H](C(C)C)N(Cc3c2)c2nccc(n2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C25H26F3N5O3S/c1-4-37(35,36)19-7-5-16(6-8-19)12-31-23(34)17-11-18-14-33(22(15(2)3)21(18)30-13-17)24-29-10-9-20(32-24)25(26,27)28/h5-11,13,15,22H,4,12,14H2,1-3H3,(H,31,34)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BK1H79
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM317853 (S-N-(4-(ethylsulfonyl)benzyl)-7-isopropyl-6-(4-(tr...) Show SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3[C@H](C(C)C)N(Cc3c2)c2nccc(n2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C25H26F3N5O3S/c1-4-37(35,36)19-7-5-16(6-8-19)12-31-23(34)17-11-18-14-33(22(15(2)3)21(18)30-13-17)24-29-10-9-20(32-24)25(26,27)28/h5-11,13,15,22H,4,12,14H2,1-3H3,(H,31,34)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...				US Patent US9624217 (2017) BindingDB Entry DOI: 10.7270/Q29P33RJ
					More data for this Ligand-Target Pair