BDBM31890 BMS270395

SMILES: CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)C(=O)Nc1ccc(cc1F)C(O)=O

InChI Key: InChIKey=AANFHDFOMFRLLR-IBGZPJMESA-N

Data: 3 Other

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 31890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic Acid Receptor, gamma (Homo sapiens (Human))	BDBM31890 (BMS270395) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)C(=O)Nc1ccc(cc1F)C(O)=O Show InChI InChI=1S/C23H26FNO4/c1-22(2)9-10-23(3,4)16-11-13(5-7-15(16)22)19(26)20(27)25-18-8-6-14(21(28)29)12-17(18)24/h5-8,11-12,19,26H,9-10H2,1-4H3,(H,25,27)(H,28,29)/t19-/m0/s1	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.9	4
CNRS					Assay Description Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...				J Mol Biol 302: 155-70 (2000) Article DOI: 10.1006/jmbi.2000.4032 BindingDB Entry DOI: 10.7270/Q2BR8QHR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoic Acid Receptor, beta (Homo sapiens (Human))	BDBM31890 (BMS270395) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)C(=O)Nc1ccc(cc1F)C(O)=O Show InChI InChI=1S/C23H26FNO4/c1-22(2)9-10-23(3,4)16-11-13(5-7-15(16)22)19(26)20(27)25-18-8-6-14(21(28)29)12-17(18)24/h5-8,11-12,19,26H,9-10H2,1-4H3,(H,25,27)(H,28,29)/t19-/m0/s1	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.9	4
CNRS					Assay Description Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...				J Mol Biol 302: 155-70 (2000) Article DOI: 10.1006/jmbi.2000.4032 BindingDB Entry DOI: 10.7270/Q2BR8QHR
					More data for this Ligand-Target Pair
Retinoic Acid Receptor, alpha (Homo sapiens (Human))	BDBM31890 (BMS270395) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)C(=O)Nc1ccc(cc1F)C(O)=O Show InChI InChI=1S/C23H26FNO4/c1-22(2)9-10-23(3,4)16-11-13(5-7-15(16)22)19(26)20(27)25-18-8-6-14(21(28)29)12-17(18)24/h5-8,11-12,19,26H,9-10H2,1-4H3,(H,25,27)(H,28,29)/t19-/m0/s1	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.9	4
CNRS					Assay Description Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...				J Mol Biol 302: 155-70 (2000) Article DOI: 10.1006/jmbi.2000.4032 BindingDB Entry DOI: 10.7270/Q2BR8QHR
					More data for this Ligand-Target Pair