BDBM318940 US10173988, Compound inventive
SMILES: Cc1ccc(cc1)N1CCN(Cc2nc(N)nc(Nc3ccc(C)c(C)c3)n2)CC1
InChI Key: InChIKey=BZFYMFCKLUAOET-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NADPH oxidase 1 (Homo sapiens (Human)) | BDBM318940 (US10173988, Compound inventive) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GLUCOX BIOTECH AB US Patent | Assay Description CHO cells modified to stably express human Nox1 were grown in DMEM/F12 gibco 31331 containing 10% FBS and 1% pen/strep at 37° C. in air with 5% CO2. ... | US Patent US10173988 (2019) BindingDB Entry DOI: 10.7270/Q2WH2S3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NADPH oxidase 4 (Homo sapiens (Human)) | BDBM318940 (US10173988, Compound inventive) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
GLUCOX BIOTECH AB US Patent | Assay Description Cells: HEK (CJ Nox4) stably expressing Nox4 was purchased from Redoxis AB (Lund). The adherent cells were cultivated in RPMI 1640 with L-Glutamine we... | US Patent US10173988 (2019) BindingDB Entry DOI: 10.7270/Q2WH2S3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM318940 (US10173988, Compound inventive) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GLUCOX BIOTECH AB US Patent | Assay Description Cells: Human blood was purchased in buffy coat, prepared the same day for isolation of neutrophils, from Labjoy AB, Lund, Sweden. Blood components we... | US Patent US10173988 (2019) BindingDB Entry DOI: 10.7270/Q2WH2S3G | |||||||||||
More data for this Ligand-Target Pair |