BDBM318943 2-[[5-(4-Cyanophenyl)quinolin-6-yl]thio]-2-methylpropanoic acid::US10173990, Example 15

SMILES: CC(C)(Sc1ccc2ncccc2c1-c1ccc(cc1)[N+]#[C-])C(O)=O

InChI Key: InChIKey=IJVXSNIZZIASBG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM318943 (2-[[5-(4-Cyanophenyl)quinolin-6-yl]thio]-2-methylp...) Show SMILES CC(C)(Sc1ccc2ncccc2c1-c1ccc(cc1)[N+]#[C-])C(O)=O Show InChI InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-17-11-10-16-15(5-4-12-22-16)18(17)13-6-8-14(21-3)9-7-13/h4-12H,1-2H3,(H,23,24)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc. US Patent					Assay Description URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...				US Patent US10173990 (2019) BindingDB Entry DOI: 10.7270/Q2RR21BP
					More data for this Ligand-Target Pair