BDBM319050 N-[(cyclopropyl- carbamoyl) methyl]-2-(2- methoxyethane- sulfonyl)-2-{6[4- (1,3-oxazol-2-yl) phenyl]-1,3- benzothiazol-2-yl} acetamide::US10173991, Example 93
SMILES: OCCCS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2ccc(cc2s1)-c1ccc(cc1)-c1ncco1
InChI Key: InChIKey=OETFXVHCNOFPKA-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelial lipase (Homo sapiens (Human)) | BDBM319050 (N-[(cyclopropyl- carbamoyl) methyl]-2-(2- methoxye...) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi... | US Patent US10173991 (2019) BindingDB Entry DOI: 10.7270/Q2N018M8 | |||||||||||
More data for this Ligand-Target Pair |