BDBM319101 N-[(cyclopropyl- carbamoyl) methyl]-2-{5- fluoro-6-[4-(1H- pyrazol-5-yl) phenyl]-1,3- benzothiazol- 2-yl}-2-(3,3,3- trifluoropropane- sulfonyl) acetamide::US10173991, Example 144

SMILES: Fc1cc2nc(sc2cc1-c1ccc(cc1)-c1ccn[nH]1)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)CCC(F)(F)F

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319101   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM319101 (N-[(cyclopropyl- carbamoyl) methyl]-2-{5- fluoro-6...) Show SMILES Fc1cc2nc(sc2cc1-c1ccc(cc1)-c1ccn[nH]1)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)CCC(F)(F)F Show InChI	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US10173991 (2019) BindingDB Entry DOI: 10.7270/Q2N018M8
					More data for this Ligand-Target Pair