BDBM31911 2-[(2,6-diaminopyrimidin-4-yl)sulfanyl]acetamide, 8
SMILES: NC(=O)CSc1cc(N)nc(N)n1
InChI Key: InChIKey=BKCXEOSYALVKFW-UHFFFAOYSA-N
Data: 1 Other
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase (IspF) (Escherichia coli (strain K12)) | BDBM31911 (2-[(2,6-diaminopyrimidin-4-yl)sulfanyl]acetamide, ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | 10 |
University of Dundee | Assay Description An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr... | J Med Chem 52: 2531-42 (2009) Article DOI: 10.1021/jm801475n BindingDB Entry DOI: 10.7270/Q23B5XGB | |||||||||||
More data for this Ligand-Target Pair |