BDBM319153 N-[(cyclopropyl- carbamoyl) methyl]-2-[5- fluoro-6-(1- methyl-1H- indazol-6-yl)-1,3- benzothiazol- 2-yl]-2- methanesulfonyl- acetamide::US10173991, Example 196

SMILES: Cn1ncc2ccc(cc12)-c1cc2sc(nc2cc1F)C(C(=O)NCC(=O)NC1CC1)S(C)(=O)=O

InChI Key: InChIKey=MCRVSPHOQBTBLT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM319153 (N-[(cyclopropyl- carbamoyl) methyl]-2-[5- fluoro-6...) Show SMILES Cn1ncc2ccc(cc12)-c1cc2sc(nc2cc1F)C(C(=O)NCC(=O)NC1CC1)S(C)(=O)=O Show InChI InChI=1S/C23H22FN5O4S2/c1-29-18-7-12(3-4-13(18)10-26-29)15-8-19-17(9-16(15)24)28-23(34-19)21(35(2,32)33)22(31)25-11-20(30)27-14-5-6-14/h3-4,7-10,14,21H,5-6,11H2,1-2H3,(H,25,31)(H,27,30)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US10173991 (2019) BindingDB Entry DOI: 10.7270/Q2N018M8
					More data for this Ligand-Target Pair