BDBM31916 Tryptophanhydroxamate, 13
SMILES: N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NO
InChI Key: InChIKey=LBMAEBPZXXNKMZ-VIFPVBQESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase (IspF) (Escherichia coli (strain K12)) | BDBM31916 (Tryptophanhydroxamate, 13) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.92E+3 | n/a | n/a | n/a | 7.0 | 10 |
University of Dundee | Assay Description An SPR assay was used to determine the binding affinities of compounds. Experiments were performed on a Biacore 3000 (Biacore, Uppsala, Sweden) instr... | J Med Chem 52: 2531-42 (2009) Article DOI: 10.1021/jm801475n BindingDB Entry DOI: 10.7270/Q23B5XGB | |||||||||||
More data for this Ligand-Target Pair |