BDBM319332 N-({[2- (benzyloxy)ethyl] carbamoyl} methyl)-2-[6-(6- fluoropyridin-3- yl)-1,3- benzothiazol- 2-yl]-2-(2- methoxyethane- sulfonyl)acetamide::US10173991, Example 377

SMILES: COCCS(=O)(=O)C(C(=O)NCC(=O)NCCOCc1ccccc1)c1nc2ccc(cc2s1)-c1ccc(F)nc1

InChI Key: InChIKey=PYWVZXOLJLOTFY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM319332 (N-({[2- (benzyloxy)ethyl] carbamoyl} methyl)-2-[6-...) Show SMILES COCCS(=O)(=O)C(C(=O)NCC(=O)NCCOCc1ccccc1)c1nc2ccc(cc2s1)-c1ccc(F)nc1 Show InChI InChI=1S/C28H29FN4O6S2/c1-38-13-14-41(36,37)26(27(35)32-17-25(34)30-11-12-39-18-19-5-3-2-4-6-19)28-33-22-9-7-20(15-23(22)40-28)21-8-10-24(29)31-16-21/h2-10,15-16,26H,11-14,17-18H2,1H3,(H,30,34)(H,32,35)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US10173991 (2019) BindingDB Entry DOI: 10.7270/Q2N018M8
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