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SMILES: FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1C(F)(F)F

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319604   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (Human))
BDBM319604
PNG
(2-[1-[[2-chloro-3- (trifluoromethyl)phenyl]methyl]...)
Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1C(F)(F)F
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent




US Patent US10174003 (2019)


Article DOI: 10.1016/j.bmcl.2005.11.052
More data for this
Ligand-Target Pair
Histone lysine demethylase PHF8


(Homo sapiens (Human))
BDBM319604
PNG
(2-[1-[[2-chloro-3- (trifluoromethyl)phenyl]methyl]...)
Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1C(F)(F)F
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent




US Patent US10174003 (2019)


Article DOI: 10.1016/j.bmcl.2005.11.052
More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (Human))
BDBM319604
PNG
(2-[1-[[2-chloro-3- (trifluoromethyl)phenyl]methyl]...)
Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1C(F)(F)F
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent




US Patent US10174003 (2019)


Article DOI: 10.1016/j.bmcl.2005.11.052
More data for this
Ligand-Target Pair