BDBM319672 2-{1-[2-(4-methylphenyl)ethyl]-1H-imidazol-4-yl}- 4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]pyridine::US10174003, Example 91::US9896436, Example 91

SMILES: Cc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1

InChI Key: InChIKey=LVTPIPCJSJQBGO-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 319672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319672 (2-{1-[2-(4-methylphenyl)ethyl]-1H-imidazol-4-yl}- ...) Show SMILES Cc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6/c1-13-2-4-14(5-3-13)7-9-29-11-17(25-12-29)16-10-15(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319672 (2-{1-[2-(4-methylphenyl)ethyl]-1H-imidazol-4-yl}- ...) Show SMILES Cc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6/c1-13-2-4-14(5-3-13)7-9-29-11-17(25-12-29)16-10-15(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM319672 (2-{1-[2-(4-methylphenyl)ethyl]-1H-imidazol-4-yl}- ...) Show SMILES Cc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6/c1-13-2-4-14(5-3-13)7-9-29-11-17(25-12-29)16-10-15(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM319672 (2-{1-[2-(4-methylphenyl)ethyl]-1H-imidazol-4-yl}- ...) Show SMILES Cc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6/c1-13-2-4-14(5-3-13)7-9-29-11-17(25-12-29)16-10-15(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of JMJD3 was determined in 384-well plate format under the following reaction conditions: 1 nM ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319672 (2-{1-[2-(4-methylphenyl)ethyl]-1H-imidazol-4-yl}- ...) Show SMILES Cc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6/c1-13-2-4-14(5-3-13)7-9-29-11-17(25-12-29)16-10-15(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319672 (2-{1-[2-(4-methylphenyl)ethyl]-1H-imidazol-4-yl}- ...) Show SMILES Cc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6/c1-13-2-4-14(5-3-13)7-9-29-11-17(25-12-29)16-10-15(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM319672 (2-{1-[2-(4-methylphenyl)ethyl]-1H-imidazol-4-yl}- ...) Show SMILES Cc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6/c1-13-2-4-14(5-3-13)7-9-29-11-17(25-12-29)16-10-15(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM319672 (2-{1-[2-(4-methylphenyl)ethyl]-1H-imidazol-4-yl}- ...) Show SMILES Cc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6/c1-13-2-4-14(5-3-13)7-9-29-11-17(25-12-29)16-10-15(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD3 was determined in 384-well plate format under the following reaction conditions: 1 nM ...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair