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BDBM319841 3-(Cyclopropylmethoxy)-N-[(1R)-1-(6-methylpyridazin-3-yl)ethyl]-5-(5-methyl-1,3-thiazol-2-yl)benzamide::US10174016, Example 8::US10202369, Example 8

SMILES: C[C@@H](NC(=O)c1cc(OCC2CC2)cc(c1)-c1ncc(C)s1)c1ccc(C)nn1

InChI Key:

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 319841   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM319841
PNG
(3-(Cyclopropylmethoxy)-N-[(1R)-1-(6-methylpyridazi...)
Show SMILES C[C@@H](NC(=O)c1cc(OCC2CC2)cc(c1)-c1ncc(C)s1)c1ccc(C)nn1 |r|
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



Bayer Aktiengesellschaft

US Patent




US Patent US10183937 (2019)


BindingDB Entry DOI: 10.7270/Q2028TNS
More data for this
Ligand-Target Pair
P2X purinoceptor 2


(Homo sapiens (Human))
BDBM319841
PNG
(3-(Cyclopropylmethoxy)-N-[(1R)-1-(6-methylpyridazi...)
Show SMILES C[C@@H](NC(=O)c1cc(OCC2CC2)cc(c1)-c1ncc(C)s1)c1ccc(C)nn1 |r|
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 90n/an/an/an/an/an/a



Bayer Aktiengesellschaft

US Patent




US Patent US10183937 (2019)


BindingDB Entry DOI: 10.7270/Q2028TNS
More data for this
Ligand-Target Pair
P2X2/3


()
BDBM319841
PNG
(3-(Cyclopropylmethoxy)-N-[(1R)-1-(6-methylpyridazi...)
Show SMILES C[C@@H](NC(=O)c1cc(OCC2CC2)cc(c1)-c1ncc(C)s1)c1ccc(C)nn1 |r|
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 90n/an/an/an/an/an/a



Bayer Aktiengesellschaft

US Patent




US Patent US10202369 (2019)

More data for this
Ligand-Target Pair
P2X purinoceptor 2


(Homo sapiens (Human))
BDBM319841
PNG
(3-(Cyclopropylmethoxy)-N-[(1R)-1-(6-methylpyridazi...)
Show SMILES C[C@@H](NC(=O)c1cc(OCC2CC2)cc(c1)-c1ncc(C)s1)c1ccc(C)nn1 |r|
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 90n/an/an/an/an/an/a



BEYER AKTIENGESELLSCHAFT

US Patent




US Patent US10174016 (2019)


BindingDB Entry DOI: 10.7270/Q2GB264F
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM319841
PNG
(3-(Cyclopropylmethoxy)-N-[(1R)-1-(6-methylpyridazi...)
Show SMILES C[C@@H](NC(=O)c1cc(OCC2CC2)cc(c1)-c1ncc(C)s1)c1ccc(C)nn1 |r|
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



Bayer Aktiengesellschaft

US Patent




US Patent US10202369 (2019)

More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM319841
PNG
(3-(Cyclopropylmethoxy)-N-[(1R)-1-(6-methylpyridazi...)
Show SMILES C[C@@H](NC(=O)c1cc(OCC2CC2)cc(c1)-c1ncc(C)s1)c1ccc(C)nn1 |r|
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



BEYER AKTIENGESELLSCHAFT

US Patent




US Patent US10174016 (2019)


BindingDB Entry DOI: 10.7270/Q2GB264F
More data for this
Ligand-Target Pair