BDBM320063 3-[(−3-hydroxybutan-2-yl)oxy]-5-(5-methyl-1,3-thiazol-2-yl)-N-{(1R)-1-[6-(trifluoromethyl)pyridazin-3-yl]ethyl}benzamide::US10174016, Example 230
SMILES: CC(O)[C@H](C)Oc1cc(cc(c1)-c1ncc(C)s1)C(=O)N[C@H](C)c1ccc(nn1)C(F)(F)F
InChI Key: InChIKey=LMHZXBDHIYABCN-YIOYIWSBSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2X purinoceptor 2 (Homo sapiens (Human)) | BDBM320063 (3-[(−3-hydroxybutan-2-yl)oxy]-5-(5-methyl-1,...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 209 | n/a | n/a | n/a | n/a | n/a | n/a |
BEYER AKTIENGESELLSCHAFT US Patent | Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati... | US Patent US10174016 (2019) BindingDB Entry DOI: 10.7270/Q2GB264F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 3 (Homo sapiens (Human)) | BDBM320063 (3-[(−3-hydroxybutan-2-yl)oxy]-5-(5-methyl-1,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
BEYER AKTIENGESELLSCHAFT US Patent | Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati... | US Patent US10174016 (2019) BindingDB Entry DOI: 10.7270/Q2GB264F | |||||||||||
More data for this Ligand-Target Pair |