null

SMILES: CCc1cnc(s1)-c1cc(OC2CCOCC2)cc(c1)C(=O)NCc1ccc(C)nn1

InChI Key: InChIKey=BZFPOECMUNEZDH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 320068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM320068 (3-(5-ethyl-1,3- thiazol-2-yl)-N-[(6- methylpyridaz...) Show SMILES CCc1cnc(s1)-c1cc(OC2CCOCC2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H26N4O3S/c1-3-21-14-25-23(31-21)17-10-16(11-20(12-17)30-19-6-8-29-9-7-19)22(28)24-13-18-5-4-15(2)26-27-18/h4-5,10-12,14,19H,3,6-9,13H2,1-2H3,(H,24,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10183937 (2019) BindingDB Entry DOI: 10.7270/Q2028TNS
					More data for this Ligand-Target Pair
P2X purinoceptor 2 (Homo sapiens (Human))	BDBM320068 (3-(5-ethyl-1,3- thiazol-2-yl)-N-[(6- methylpyridaz...) Show SMILES CCc1cnc(s1)-c1cc(OC2CCOCC2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H26N4O3S/c1-3-21-14-25-23(31-21)17-10-16(11-20(12-17)30-19-6-8-29-9-7-19)22(28)24-13-18-5-4-15(2)26-27-18/h4-5,10-12,14,19H,3,6-9,13H2,1-2H3,(H,24,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10183937 (2019) BindingDB Entry DOI: 10.7270/Q2028TNS
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM320068 (3-(5-ethyl-1,3- thiazol-2-yl)-N-[(6- methylpyridaz...) Show SMILES CCc1cnc(s1)-c1cc(OC2CCOCC2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H26N4O3S/c1-3-21-14-25-23(31-21)17-10-16(11-20(12-17)30-19-6-8-29-9-7-19)22(28)24-13-18-5-4-15(2)26-27-18/h4-5,10-12,14,19H,3,6-9,13H2,1-2H3,(H,24,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
BEYER AKTIENGESELLSCHAFT US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10174016 (2019) BindingDB Entry DOI: 10.7270/Q2GB264F
					More data for this Ligand-Target Pair
P2X purinoceptor 2/3 (Homo sapiens (Human))	BDBM320068 (3-(5-ethyl-1,3- thiazol-2-yl)-N-[(6- methylpyridaz...) Show SMILES CCc1cnc(s1)-c1cc(OC2CCOCC2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H26N4O3S/c1-3-21-14-25-23(31-21)17-10-16(11-20(12-17)30-19-6-8-29-9-7-19)22(28)24-13-18-5-4-15(2)26-27-18/h4-5,10-12,14,19H,3,6-9,13H2,1-2H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...				US Patent US10472354 (2019) BindingDB Entry DOI: 10.7270/Q2KD2197
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM320068 (3-(5-ethyl-1,3- thiazol-2-yl)-N-[(6- methylpyridaz...) Show SMILES CCc1cnc(s1)-c1cc(OC2CCOCC2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H26N4O3S/c1-3-21-14-25-23(31-21)17-10-16(11-20(12-17)30-19-6-8-29-9-7-19)22(28)24-13-18-5-4-15(2)26-27-18/h4-5,10-12,14,19H,3,6-9,13H2,1-2H3,(H,24,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10202369 (2019) BindingDB Entry DOI: 10.7270/Q2TT4T2P
					More data for this Ligand-Target Pair
P2X purinoceptor 2/3 (Homo sapiens (Human))	BDBM320068 (3-(5-ethyl-1,3- thiazol-2-yl)-N-[(6- methylpyridaz...) Show SMILES CCc1cnc(s1)-c1cc(OC2CCOCC2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H26N4O3S/c1-3-21-14-25-23(31-21)17-10-16(11-20(12-17)30-19-6-8-29-9-7-19)22(28)24-13-18-5-4-15(2)26-27-18/h4-5,10-12,14,19H,3,6-9,13H2,1-2H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10202369 (2019) BindingDB Entry DOI: 10.7270/Q2TT4T2P
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM320068 (3-(5-ethyl-1,3- thiazol-2-yl)-N-[(6- methylpyridaz...) Show SMILES CCc1cnc(s1)-c1cc(OC2CCOCC2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H26N4O3S/c1-3-21-14-25-23(31-21)17-10-16(11-20(12-17)30-19-6-8-29-9-7-19)22(28)24-13-18-5-4-15(2)26-27-18/h4-5,10-12,14,19H,3,6-9,13H2,1-2H3,(H,24,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...				US Patent US10472354 (2019) BindingDB Entry DOI: 10.7270/Q2KD2197
					More data for this Ligand-Target Pair
P2X purinoceptor 2 (Homo sapiens (Human))	BDBM320068 (3-(5-ethyl-1,3- thiazol-2-yl)-N-[(6- methylpyridaz...) Show SMILES CCc1cnc(s1)-c1cc(OC2CCOCC2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H26N4O3S/c1-3-21-14-25-23(31-21)17-10-16(11-20(12-17)30-19-6-8-29-9-7-19)22(28)24-13-18-5-4-15(2)26-27-18/h4-5,10-12,14,19H,3,6-9,13H2,1-2H3,(H,24,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
BEYER AKTIENGESELLSCHAFT US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10174016 (2019) BindingDB Entry DOI: 10.7270/Q2GB264F
					More data for this Ligand-Target Pair