BDBM320258 N-(2-carboxyindol-5-yl)-2-(4-(5-chloro-2-(1H-tetrazol-1-yl)phenyl))-2-oxo-pyridin-1-yl)acetamide ::US10174020, Compound 6

SMILES: CC(C)(C)OC(=O)c1cc2cc(NC(=O)Cn3ccc(cc3=O)-c3cc(Cl)ccc3-n3cnnn3)ccc2[nH]1

InChI Key: InChIKey=FYJMLBSKCKPKGN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XI (Homo sapiens (Human))	BDBM320258 (N-(2-carboxyindol-5-yl)-2-(4-(5-chloro-2-(1H-tetra...) Show SMILES CC(C)(C)OC(=O)c1cc2cc(NC(=O)Cn3ccc(cc3=O)-c3cc(Cl)ccc3-n3cnnn3)ccc2[nH]1 Show InChI InChI=1S/C27H24ClN7O4/c1-27(2,3)39-26(38)22-11-17-10-19(5-6-21(17)31-22)30-24(36)14-34-9-8-16(12-25(34)37)20-13-18(28)4-7-23(20)35-15-29-32-33-35/h4-13,15,31H,14H2,1-3H3,(H,30,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SICHUAN HAISCO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...				US Patent US10174020 (2019) BindingDB Entry DOI: 10.7270/Q2BK1FGM
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