BDBM32060 MLS000053494::SMR000063563::[4-(4-hydroxyphenyl)-1-piperazinyl]-(2-naphthalenyl)methanone::[4-(4-hydroxyphenyl)piperazin-1-yl]-naphthalen-2-yl-methanone::[4-(4-hydroxyphenyl)piperazin-1-yl]-naphthalen-2-ylmethanone::[4-(4-hydroxyphenyl)piperazino]-(2-naphthyl)methanone::cid_2120761

SMILES: Oc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=JQPVGLUWXLZHRL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Large T antigen (Simian virus 40)	BDBM32060 (MLS000053494 | SMR000063563 | [4-(4-hydroxyphenyl)...) Show SMILES Oc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C21H20N2O2/c24-20-9-7-19(8-10-20)22-11-13-23(14-12-22)21(25)18-6-5-16-3-1-2-4-17(16)15-18/h1-10,15,24H,11-14H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	9.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Specialized Biocontainment Screening Center Curated by PubChem BioAssay					Assay Description A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M61HQ8
					More data for this Ligand-Target Pair
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM32060 (MLS000053494 | SMR000063563 | [4-(4-hydroxyphenyl)...) Show SMILES Oc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C21H20N2O2/c24-20-9-7-19(8-10-20)22-11-13-23(14-12-22)21(25)18-6-5-16-3-1-2-4-17(16)15-18/h1-10,15,24H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	7.4	23
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2Q23XM6
					More data for this Ligand-Target Pair