new BindingDB logo
myBDB logout

BDBM32060 MLS000053494::SMR000063563::[4-(4-hydroxyphenyl)-1-piperazinyl]-(2-naphthalenyl)methanone::[4-(4-hydroxyphenyl)piperazin-1-yl]-naphthalen-2-yl-methanone::[4-(4-hydroxyphenyl)piperazin-1-yl]-naphthalen-2-ylmethanone::[4-(4-hydroxyphenyl)piperazino]-(2-naphthyl)methanone::cid_2120761

SMILES: Oc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=JQPVGLUWXLZHRL-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 32060   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Heat shock protein HSP90


(Homo sapiens (human))
BDBM32060
PNG
(MLS000053494 | SMR000063563 | [4-(4-hydroxyphenyl)...)
Show SMILES Oc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H20N2O2/c24-20-9-7-19(8-10-20)22-11-13-23(14-12-22)21(25)18-6-5-16-3-1-2-4-17(16)15-18/h1-10,15,24H,11-14H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 5.00E+4n/an/an/an/a7.423



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...


PubChem Bioassay (2007)

More data for this
Ligand-Target Pair
phosphomevalonate kinase


(Streptococcus pneumoniae D39)
BDBM32060
PNG
(MLS000053494 | SMR000063563 | [4-(4-hydroxyphenyl)...)
Show SMILES Oc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H20N2O2/c24-20-9-7-19(8-10-20)22-11-13-23(14-12-22)21(25)18-6-5-16-3-1-2-4-17(16)15-18/h1-10,15,24H,11-14H2
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a>1.00E+7n/an/an/an/an/an/a



SRMLSC

Curated by PubChem BioAssay


Assay Description
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...


Citation and Details
More data for this
Ligand-Target Pair
large T antigen


(Simian virus 40)
BDBM32060
PNG
(MLS000053494 | SMR000063563 | [4-(4-hydroxyphenyl)...)
Show SMILES Oc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H20N2O2/c24-20-9-7-19(8-10-20)22-11-13-23(14-12-22)21(25)18-6-5-16-3-1-2-4-17(16)15-18/h1-10,15,24H,11-14H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 9.84E+3n/an/an/an/an/an/a



Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay


Assay Description
A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...


Citation and Details
More data for this
Ligand-Target Pair
phosphomevalonate kinase


(Streptococcus pneumoniae D39)
BDBM32060
PNG
(MLS000053494 | SMR000063563 | [4-(4-hydroxyphenyl)...)
Show SMILES Oc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H20N2O2/c24-20-9-7-19(8-10-20)22-11-13-23(14-12-22)21(25)18-6-5-16-3-1-2-4-17(16)15-18/h1-10,15,24H,11-14H2
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a>1.00E+7n/an/an/an/an/an/a



SRMLSC

Curated by PubChem BioAssay


Assay Description
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...


Citation and Details
More data for this
Ligand-Target Pair
phosphomevalonate kinase


(Streptococcus pneumoniae D39)
BDBM32060
PNG
(MLS000053494 | SMR000063563 | [4-(4-hydroxyphenyl)...)
Show SMILES Oc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H20N2O2/c24-20-9-7-19(8-10-20)22-11-13-23(14-12-22)21(25)18-6-5-16-3-1-2-4-17(16)15-18/h1-10,15,24H,11-14H2
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a>1.00E+7n/an/an/an/an/an/a



SRMLSC

Curated by PubChem BioAssay


Assay Description
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...


Citation and Details
More data for this
Ligand-Target Pair