null
SMILES: CN(Cc1cc(OC(F)(F)c2ccccc2)n(CC2CCCCC2)n1)C(=O)OC(C)(C)C
InChI Key: InChIKey=CQNJEXYKLPRKIE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM322112 (1-{1-(Cyclohexylmethyl)-5-[difluoro(phenyl)methoxy...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent | Assay Description The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe... | US Patent US10183913 (2019) BindingDB Entry DOI: 10.7270/Q2MW2K73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM322112 (1-{1-(Cyclohexylmethyl)-5-[difluoro(phenyl)methoxy...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent | Assay Description A solution of 200 μL in total was prepared by mixing 50 μL of [3H] mesulergine (manufactured by GE Healthcare) diluted with 50 mmol/L Tris-... | US Patent US10183913 (2019) BindingDB Entry DOI: 10.7270/Q2MW2K73 | |||||||||||
More data for this Ligand-Target Pair |