BDBM322382 (R)-N-(2,2-dimethylquinuclidin-3-yl)-8,9-dihydro-7H-thieno[2,3-f]chromene-2-carboxamide::US10183938, Compound (R)-145
SMILES: CC1(C)[C@H](NC(=O)c2cc3ccc4OCCCc4c3s2)C2CCN1CC2
InChI Key: InChIKey=XPUCDKPVZLZWDD-LJQANCHMSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor protein alpha-7 subunit (Homo sapiens (Human)) | BDBM322382 ((R)-N-(2,2-dimethylquinuclidin-3-yl)-8,9-dihydro-7...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axovant Sciences GmbH US Patent | Assay Description The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp... | US Patent US10183938 (2019) BindingDB Entry DOI: 10.7270/Q2VD71JR | |||||||||||
More data for this Ligand-Target Pair |