BDBM322385 (R)-6-chloro-N-(2,2-dimethylquinuclidin-3-yl)-7-methylbenzo[b]thiophene-2-carboxamide::US10183938, Compound (R)-148
SMILES: Cc1c(Cl)ccc2cc(sc12)C(=O)N[C@@H]1C2CCN(CC2)C1(C)C
InChI Key: InChIKey=VWQHJDJSFBFAOU-QGZVFWFLSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor protein alpha-7 subunit (Homo sapiens (Human)) | BDBM322385 ((R)-6-chloro-N-(2,2-dimethylquinuclidin-3-yl)-7-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axovant Sciences GmbH US Patent | Assay Description The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp... | US Patent US10183938 (2019) BindingDB Entry DOI: 10.7270/Q2VD71JR | |||||||||||
More data for this Ligand-Target Pair |