BDBM323028 (1R,2R or 1S,2S)-N-(3-Cyano-1-methyl- 1H-pyrazol-4-yl)-2-[4-(1H-pyrazol-3- yl)benzoyl]cyclohexanecarboxamide::US10183947, Example 12::US10508119, Example 12

SMILES: Cn1cc(NC(=O)C2CCCCC2C(=O)c2ccc(cc2)-c2cc[nH]n2)c(n1)C#N

InChI Key:

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM323028 ((1R,2R or 1S,2S)-N-(3-Cyano-1-methyl- 1H-pyrazol-4...) Show SMILES Cn1cc(NC(=O)C2CCCCC2C(=O)c2ccc(cc2)-c2cc[nH]n2)c(n1)C#N |w:7.6,12.13| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
ASTRAZENECA AB US Patent					Assay Description Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...				US Patent US10508119 (2019) BindingDB Entry DOI: 10.7270/Q2FB55BJ
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM323028 ((1R,2R or 1S,2S)-N-(3-Cyano-1-methyl- 1H-pyrazol-4...) Show SMILES Cn1cc(NC(=O)C2CCCCC2C(=O)c2ccc(cc2)-c2cc[nH]n2)c(n1)C#N |w:7.6,12.13| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
ASTRAZENECA AB US Patent					Assay Description Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...				US Patent US10183947 (2019) BindingDB Entry DOI: 10.7270/Q22Z17M7
					More data for this Ligand-Target Pair