BDBM323305 US9630956, Compound I-42
SMILES: CC(C)n1cc(ccc1=O)-c1cnc(N)c(n1)-c1nnc(o1)-c1cccc(c1)C(C)N
InChI Key: InChIKey=LFZYWOATIVPYAQ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM323305 (US9630956, Compound I-42) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Incorporated US Patent | Assay Description Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu... | US Patent US9630956 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q2S | |||||||||||
More data for this Ligand-Target Pair |