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SMILES: CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1ccccc1

InChI Key: InChIKey=MVARWKBWYZIQEA-OAQYLSRUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323638 ((R)-N-benzyl-2-(3-(2- ethoxyphenoxy)piperidin- 1-y...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C25H28N4O3/c1-2-31-22-12-6-7-13-23(22)32-21-11-8-14-29(18-21)25-27-16-20(17-28-25)24(30)26-15-19-9-4-3-5-10-19/h3-7,9-10,12-13,16-17,21H,2,8,11,14-15,18H2,1H3,(H,26,30)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323638 ((R)-N-benzyl-2-(3-(2- ethoxyphenoxy)piperidin- 1-y...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C25H28N4O3/c1-2-31-22-12-6-7-13-23(22)32-21-11-8-14-29(18-21)25-27-16-20(17-28-25)24(30)26-15-19-9-4-3-5-10-19/h3-7,9-10,12-13,16-17,21H,2,8,11,14-15,18H2,1H3,(H,26,30)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US10188653 (2019) BindingDB Entry DOI: 10.7270/Q28G8NS4
					More data for this Ligand-Target Pair