null

SMILES: CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1Cc2ccccc2C1

InChI Key: InChIKey=QUTKPSJOIWGKIA-JOCHJYFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323644 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C26H28N4O3/c1-2-32-23-11-5-6-12-24(23)33-22-10-7-13-29(18-22)26-27-14-21(15-28-26)25(31)30-16-19-8-3-4-9-20(19)17-30/h3-6,8-9,11-12,14-15,22H,2,7,10,13,16-18H2,1H3/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323644 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C26H28N4O3/c1-2-32-23-11-5-6-12-24(23)33-22-10-7-13-29(18-22)26-27-14-21(15-28-26)25(31)30-16-19-8-3-4-9-20(19)17-30/h3-6,8-9,11-12,14-15,22H,2,7,10,13,16-18H2,1H3/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US10188653 (2019) BindingDB Entry DOI: 10.7270/Q28G8NS4
					More data for this Ligand-Target Pair