null

SMILES: CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CC(C1)Oc1ccccc1

InChI Key: InChIKey=LXSGWMQGIMDSGC-JOCHJYFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323669 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CC(C1)Oc1ccccc1 Show InChI InChI=1S/C27H30N4O4/c1-2-33-24-12-6-7-13-25(24)35-22-11-8-14-30(17-22)27-28-15-20(16-29-27)26(32)31-18-23(19-31)34-21-9-4-3-5-10-21/h3-7,9-10,12-13,15-16,22-23H,2,8,11,14,17-19H2,1H3/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323669 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CC(C1)Oc1ccccc1 Show InChI InChI=1S/C27H30N4O4/c1-2-33-24-12-6-7-13-25(24)35-22-11-8-14-30(17-22)27-28-15-20(16-29-27)26(32)31-18-23(19-31)34-21-9-4-3-5-10-21/h3-7,9-10,12-13,15-16,22-23H,2,8,11,14,17-19H2,1H3/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US10188653 (2019) BindingDB Entry DOI: 10.7270/Q28G8NS4
					More data for this Ligand-Target Pair