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SMILES: Cc1ncn(n1)-c1ccc(C(=O)NC[C@@H](c2cccc(F)c2)c2nc3c(F)ccc(C)c3c(=O)[nH]2)c(Cl)c1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324249   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor IX


(Homo sapiens (Human))		BDBM324249
PNG
(US10189819, Example 103)
Show SMILES Cc1ncn(n1)-c1ccc(C(=O)NC[C@@H](c2cccc(F)c2)c2nc3c(F)ccc(C)c3c(=O)[nH]2)c(Cl)c1 |r|
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PC cid
PC sid
UniChem
US Patent
n/an/a 6.35n/an/an/an/an/an/a



Merck Sharp & Dohme, Corp.; Mochida Paraceuticals Co., Ltd.

US Patent


Assay Description
Formation of a clot to stem bleeding at a site of blood vessel injury involves the coordinated activity of a group of plasma proteins that initiate a...

US Patent US10189819 (2019)


BindingDB Entry DOI: 10.7270/Q200046Z
More data for this
Ligand-Target Pair