BDBM324406 US10189835, Compound 587

SMILES: CN(O)C(=O)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1

InChI Key: InChIKey=FSIRKUPBVXWJCA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Capsid protein (Hepatitis B virus genotype C subtype ayr (isolate ...)	BDBM324406 (US10189835, Compound 587) Show SMILES CN(O)C(=O)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C15H16ClN5O3/c1-20(24)14(22)13-11-8-21(6-5-12(11)18-19-13)15(23)17-10-4-2-3-9(16)7-10/h2-4,7,24H,5-6,8H2,1H3,(H,17,23)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
NOVIRA THERAPEUTICS, INC. US Patent					Assay Description HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...				US Patent US10189835 (2019) BindingDB Entry DOI: 10.7270/Q2KP8482
					More data for this Ligand-Target Pair