BDBM324809 9-(4-(2H-1,2,3-triazol-2-::US10189841, Compound I-15::US10399980, Compound I-15
SMILES: CC(C)Oc1cc(F)ccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3nccn3)c2n1
InChI Key: InChIKey=TZYDFUSRSPJZKB-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human)) | BDBM324809 (9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FORMA Therapeutics, Inc. US Patent | Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning... | US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human)) | BDBM324809 (9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
FORMA Therapeutics, Inc. US Patent | Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning... | US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR | |||||||||||
More data for this Ligand-Target Pair |