BDBM324811 9-(4-(1H-pyrazol-1-::US10189841, Compound I-17::US10399980, Compound I-17

SMILES: CC(C)c1ccncc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-n3cccn3)c2n1

InChI Key: InChIKey=CAJYQOLRJOWKKY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 324811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324811 (9-(4-(1H-pyrazol-1- | US10189841, Compound I-17 | ...) Show SMILES CC(C)c1ccncc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-n3cccn3)c2n1 Show InChI InChI=1S/C24H23N7O/c1-16(2)19-9-11-25-13-20(19)22-26-14-21-23(28-22)30(24(32)29(21)3)15-17-5-7-18(8-6-17)31-12-4-10-27-31/h4-14,16H,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324811 (9-(4-(1H-pyrazol-1- | US10189841, Compound I-17 | ...) Show SMILES CC(C)c1ccncc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-n3cccn3)c2n1 Show InChI InChI=1S/C24H23N7O/c1-16(2)19-9-11-25-13-20(19)22-26-14-21-23(28-22)30(24(32)29(21)3)15-17-5-7-18(8-6-17)31-12-4-10-27-31/h4-14,16H,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324811 (9-(4-(1H-pyrazol-1- | US10189841, Compound I-17 | ...) Show SMILES CC(C)c1ccncc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-n3cccn3)c2n1 Show InChI InChI=1S/C24H23N7O/c1-16(2)19-9-11-25-13-20(19)22-26-14-21-23(28-22)30(24(32)29(21)3)15-17-5-7-18(8-6-17)31-12-4-10-27-31/h4-14,16H,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair