BDBM324938 2-(2-isopropylphenyl)-9-(1-::US10189841, Compound I-144::US10399980, Compound I-144

SMILES: CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(C3CCN(CC3)c3cccnc3)c2n1

InChI Key: InChIKey=AYDLXHQGLQSMJV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 324938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324938 (2-(2-isopropylphenyl)-9-(1- | US10189841, Compound...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(C3CCN(CC3)c3cccnc3)c2n1 Show InChI InChI=1S/C24H26N6O/c1-16(2)19-7-3-4-8-20(19)22-26-15-21-23(28-22)30(24(31)27-21)17-9-12-29(13-10-17)18-6-5-11-25-14-18/h3-8,11,14-17H,9-10,12-13H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324938 (2-(2-isopropylphenyl)-9-(1- | US10189841, Compound...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(C3CCN(CC3)c3cccnc3)c2n1 Show InChI InChI=1S/C24H26N6O/c1-16(2)19-7-3-4-8-20(19)22-26-15-21-23(28-22)30(24(31)27-21)17-9-12-29(13-10-17)18-6-5-11-25-14-18/h3-8,11,14-17H,9-10,12-13H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair