BDBM325079 2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H-::US10189841, Compound I-285::US10189841, Compound I-298::US10399980, Compound I-285

SMILES: CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3cnnn3C)c2n1

InChI Key: InChIKey=KEYQNLYNEOYIKI-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 325079   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325079 (2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H- ...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3cnnn3C)c2n1 Show InChI InChI=1S/C25H25N7O/c1-16(2)19-7-5-6-8-20(19)23-26-13-22-24(28-23)32(25(33)30(22)3)15-17-9-11-18(12-10-17)21-14-27-29-31(21)4/h5-14,16H,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325079 (2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H- ...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3cnnn3C)c2n1 Show InChI InChI=1S/C25H25N7O/c1-16(2)19-7-5-6-8-20(19)23-26-13-22-24(28-23)32(25(33)30(22)3)15-17-9-11-18(12-10-17)21-14-27-29-31(21)4/h5-14,16H,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325079 (2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H- ...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3cnnn3C)c2n1 Show InChI InChI=1S/C25H25N7O/c1-16(2)19-7-5-6-8-20(19)23-26-13-22-24(28-23)32(25(33)30(22)3)15-17-9-11-18(12-10-17)21-14-27-29-31(21)4/h5-14,16H,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325079 (2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H- ...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3cnnn3C)c2n1 Show InChI InChI=1S/C25H25N7O/c1-16(2)19-7-5-6-8-20(19)23-26-13-22-24(28-23)32(25(33)30(22)3)15-17-9-11-18(12-10-17)21-14-27-29-31(21)4/h5-14,16H,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair