BDBM325132 9-(4-(4-(2-aminopropan-2-yl)-1H-1,2,3-triazol-1-::US10189841, Compound I-338::US10399980, Compound I-338

SMILES: CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cc(nn3)C(C)(C)N)c2n1

InChI Key: InChIKey=RLIUDQXNETWJQR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325132 (9-(4-(4-(2-aminopropan-2-yl)-1H-1,2,3-triazol-1- |...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cc(nn3)C(C)(C)N)c2n1 Show InChI InChI=1S/C26H28N8O/c1-16(2)19-7-5-6-8-20(19)23-28-13-21-24(30-23)33(25(35)29-21)14-17-9-11-18(12-10-17)34-15-22(31-32-34)26(3,4)27/h5-13,15-16H,14,27H2,1-4H3,(H,29,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325132 (9-(4-(4-(2-aminopropan-2-yl)-1H-1,2,3-triazol-1- |...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cc(nn3)C(C)(C)N)c2n1 Show InChI InChI=1S/C26H28N8O/c1-16(2)19-7-5-6-8-20(19)23-28-13-21-24(30-23)33(25(35)29-21)14-17-9-11-18(12-10-17)34-15-22(31-32-34)26(3,4)27/h5-13,15-16H,14,27H2,1-4H3,(H,29,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair