BDBM325272 N-isopropyl-4-((2-::US10189841, Compound I-478::US10399980, Compound I-478

SMILES: CC(C)NC(=O)N1CCC(Cn2c3nc(ncc3n(C)c2=O)-c2ccccc2C(C)C)CC1

InChI Key: InChIKey=XMFJBFJFTBSZQO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325272 (N-isopropyl-4-((2- | US10189841, Compound I-478 | ...) Show SMILES CC(C)NC(=O)N1CCC(Cn2c3nc(ncc3n(C)c2=O)-c2ccccc2C(C)C)CC1 Show InChI InChI=1S/C25H34N6O2/c1-16(2)19-8-6-7-9-20(19)22-26-14-21-23(28-22)31(25(33)29(21)5)15-18-10-12-30(13-11-18)24(32)27-17(3)4/h6-9,14,16-18H,10-13,15H2,1-5H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325272 (N-isopropyl-4-((2- | US10189841, Compound I-478 | ...) Show SMILES CC(C)NC(=O)N1CCC(Cn2c3nc(ncc3n(C)c2=O)-c2ccccc2C(C)C)CC1 Show InChI InChI=1S/C25H34N6O2/c1-16(2)19-8-6-7-9-20(19)22-26-14-21-23(28-22)31(25(33)29(21)5)15-18-10-12-30(13-11-18)24(32)27-17(3)4/h6-9,14,16-18H,10-13,15H2,1-5H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair