BDBM325303 US10189841, Compound I-509::US10399980, Compound I-509

SMILES: CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ncc(cn3)-n3cccn3)c2n1

InChI Key: InChIKey=LPYBILDUTWVADS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325303 (US10189841, Compound I-509 | US10399980, Compound ...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ncc(cn3)-n3cccn3)c2n1 Show InChI InChI=1S/C22H20N8O/c1-14(2)16-6-3-4-7-17(16)20-25-12-18-21(28-20)29(22(31)27-18)13-19-23-10-15(11-24-19)30-9-5-8-26-30/h3-12,14H,13H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325303 (US10189841, Compound I-509 | US10399980, Compound ...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ncc(cn3)-n3cccn3)c2n1 Show InChI InChI=1S/C22H20N8O/c1-14(2)16-6-3-4-7-17(16)20-25-12-18-21(28-20)29(22(31)27-18)13-19-23-10-15(11-24-19)30-9-5-8-26-30/h3-12,14H,13H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair