BDBM3260 4-Anilino quinazoline deriv. 11::N-methyl-N-phenylquinazolin-4-amine
SMILES: CN(c1ccccc1)c1ncnc2ccccc12
InChI Key: InChIKey=VCLXUEIYTZFLMO-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM3260 (4-Anilino quinazoline deriv. 11 | N-methyl-N-pheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Auckland | Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe... | J Med Chem 38: 3482-7 (1995) Article DOI: 10.1021/jm00018a008 BindingDB Entry DOI: 10.7270/Q2319T3K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM3260 (4-Anilino quinazoline deriv. 11 | N-methyl-N-pheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism towards Epidermal growth factor receptor | Bioorg Med Chem Lett 7: 421-424 (1997) Article DOI: 10.1016/S0960-894X(97)00035-8 BindingDB Entry DOI: 10.7270/Q2SB45RN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony stimulating factor receptor (Homo sapiens (Human)) | BDBM3260 (4-Anilino quinazoline deriv. 11 | N-methyl-N-pheny...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism towards Colony stimulating factor 1 receptor (CSF-1R) | Bioorg Med Chem Lett 7: 421-424 (1997) Article DOI: 10.1016/S0960-894X(97)00035-8 BindingDB Entry DOI: 10.7270/Q2SB45RN | |||||||||||
More data for this Ligand-Target Pair |