BDBM326269 US9637488, 29

SMILES: Nc1ncnc(N2CCCC2c2cc3ccc(F)cc3nc2-c2ccccc2)c1C#C

InChI Key: InChIKey=BYNNHQZAAJKNJQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM326269 (US9637488, 29) Show SMILES Nc1ncnc(N2CCCC2c2cc3ccc(F)cc3nc2-c2ccccc2)c1C#C Show InChI InChI=1S/C25H20FN5/c1-2-19-24(27)28-15-29-25(19)31-12-6-9-22(31)20-13-17-10-11-18(26)14-21(17)30-23(20)16-7-4-3-5-8-16/h1,3-5,7-8,10-11,13-15,22H,6,9,12H2,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Exemplary compounds of the invention were tested their inhibitory activity or potency against PI3Kδ in 10-dose IC50 mode with 3-fold serial dilu...				US Patent US9637488 (2017) BindingDB Entry DOI: 10.7270/Q2D220Q6
					More data for this Ligand-Target Pair