BDBM326284 US9637488, 67

SMILES: Nc1ncnc(N2CCCC2c2cc3cccc(Cl)c3nc2-c2ccccc2)c1C#N

InChI Key: InChIKey=VMRLPOCRAZRSGL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM326284 (US9637488, 67) Show SMILES Nc1ncnc(N2CCCC2c2cc3cccc(Cl)c3nc2-c2ccccc2)c1C#N Show InChI InChI=1S/C24H19ClN6/c25-19-9-4-8-16-12-17(21(30-22(16)19)15-6-2-1-3-7-15)20-10-5-11-31(20)24-18(13-26)23(27)28-14-29-24/h1-4,6-9,12,14,20H,5,10-11H2,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0500	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Exemplary compounds of the invention were tested their inhibitory activity or potency against PI3Kδ in 10-dose IC50 mode with 3-fold serial dilu...				US Patent US9637488 (2017) BindingDB Entry DOI: 10.7270/Q2D220Q6
					More data for this Ligand-Target Pair