BDBM326285 US9637488, 68

SMILES: Nc1nc(N)c(C#N)c(n1)N1CCCC1c1cc2cccc(Cl)c2nc1-c1ccccc1

InChI Key: InChIKey=ZEETWNTVVBGPEV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM326285 (US9637488, 68) Show SMILES Nc1nc(N)c(C#N)c(n1)N1CCCC1c1cc2cccc(Cl)c2nc1-c1ccccc1 Show InChI InChI=1S/C24H20ClN7/c25-18-9-4-8-15-12-16(20(29-21(15)18)14-6-2-1-3-7-14)19-10-5-11-32(19)23-17(13-26)22(27)30-24(28)31-23/h1-4,6-9,12,19H,5,10-11H2,(H4,27,28,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0500	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Exemplary compounds of the invention were tested their inhibitory activity or potency against PI3Kδ in 10-dose IC50 mode with 3-fold serial dilu...				US Patent US9637488 (2017) BindingDB Entry DOI: 10.7270/Q2D220Q6
					More data for this Ligand-Target Pair