BDBM32639 amino-oxazole, 2
SMILES: Nc1ncc(o1)C(=O)c1cccc(Br)c1
InChI Key: InChIKey=YDCMMVTWXORJGO-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Biotin Carboxylase (Escherichia coli (strain K12)) | BDBM32639 (amino-oxazole, 2) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem | DrugBank MMDB PDB Article PubMed | n/a | n/a | 2.15E+4 | n/a | n/a | n/a | n/a | 8.0 | 23 |
Pfizer | Assay Description Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla... | ACS Chem Biol 4: 473-83 (2009) Article DOI: 10.1021/cb9000102 BindingDB Entry DOI: 10.7270/Q2WM1BR8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |