null
SMILES: CC1(C)CC(=O)c2c(N)ncnc2C1
InChI Key: InChIKey=DYPFWRCGECJCBK-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Biotin carboxylase (Escherichia coli (strain K12)) | BDBM32643 (amino pyrimidine ketone, 3) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem | DrugBank MMDB PDB Article PubMed | n/a | n/a | 6.08E+4 | n/a | n/a | n/a | n/a | 8.0 | 23 |
Pfizer | Assay Description Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla... | ACS Chem Biol 4: 473-83 (2009) Article DOI: 10.1021/cb9000102 BindingDB Entry DOI: 10.7270/Q2WM1BR8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |