BDBM328996 1137477-07-6::US9663503, Compound Y-081
SMILES: COC(=O)c1cnc(Nc2cnc(cn2)C#N)cc1NCC1CNCCO1
InChI Key: InChIKey=PHPWNBVMNTWSJB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM328996 (1137477-07-6 | US9663503, Compound Y-081) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Cancer Research Technology Limited US Patent | Assay Description CHK1 kinase activity was measured in a microfluidic assay that monitors the separation of a phosphorylated product from its substrate. The assay was ... | US Patent US9663503 (2017) BindingDB Entry DOI: 10.7270/Q2T43W7G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |