BDBM329008 1137477-35-0::US9663503, Compound Y-102

SMILES: O=C(Nc1ccccc1)c1cnc(Nc2cnc(cn2)C#N)cc1NCC1CNCCO1

InChI Key: InChIKey=WSTAZAZSYYTWAC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM329008 (1137477-35-0 | US9663503, Compound Y-102) Show SMILES O=C(Nc1ccccc1)c1cnc(Nc2cnc(cn2)C#N)cc1NCC1CNCCO1 Show InChI InChI=1S/C22H22N8O2/c23-9-16-10-27-21(14-25-16)30-20-8-19(26-12-17-11-24-6-7-32-17)18(13-28-20)22(31)29-15-4-2-1-3-5-15/h1-5,8,10,13-14,17,24H,6-7,11-12H2,(H,29,31)(H2,26,27,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description CHK1 kinase activity was measured in a microfluidic assay that monitors the separation of a phosphorylated product from its substrate. The assay was ...				US Patent US9663503 (2017) BindingDB Entry DOI: 10.7270/Q2T43W7G
					More data for this Ligand-Target Pair