Found 2 hits for monomerid = 329645 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Nuclear receptor ROR-gamma
(Homo sapiens (Human)) | BDBM329645
((S)-7-ethyl-N¿((R)-1-(4-(ethylsulfonyl)phenyl)-2-m...)Show SMILES CC[C@@H]1N(C[C@H]2CC[C@@H](CC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](COC)c1ccc(cc1)S(=O)(=O)CC |r,wU:25.27,8.11,wD:2.1,5.4,(-5.94,-18.02,;-4.43,-17.7,;-3.95,-16.24,;-4.86,-14.99,;-6.4,-14.99,;-7.17,-13.66,;-6.4,-12.33,;-7.17,-10.99,;-8.71,-10.99,;-9.48,-12.33,;-8.71,-13.66,;-9.48,-9.66,;-8.71,-8.32,;-11.02,-9.66,;-10.25,-8.32,;-3.95,-13.75,;-2.49,-14.22,;-1.16,-13.45,;.18,-14.22,;.18,-15.76,;-1.16,-16.53,;-2.49,-15.76,;1.51,-13.45,;1.51,-11.91,;2.85,-14.22,;4.18,-13.45,;4.18,-11.91,;5.51,-11.14,;5.51,-9.6,;5.51,-14.22,;5.51,-15.76,;6.85,-16.53,;7.91,-15.61,;8.18,-14.22,;6.85,-13.45,;9.11,-16.3,;8.42,-17.5,;9.8,-15.1,;10.3,-16.99,;11.5,-16.3,)| Show InChI InChI=1S/C29H38F3N3O4S/c1-4-26-27-22(17-35(26)16-19-6-10-23(11-7-19)29(30,31)32)14-21(15-33-27)28(36)34-25(18-39-3)20-8-12-24(13-9-20)40(37,38)5-2/h8-9,12-15,19,23,25-26H,4-7,10-11,16-18H2,1-3H3,(H,34,36)/t19-,23-,25-,26-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| <100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharmaceuticals, LLC
US Patent
| Assay Description
Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li... |
US Patent US11001583 (2021)
BindingDB Entry DOI: 10.7270/Q2JW8J06 |
More data for this
Ligand-Target Pair | |
Nuclear receptor ROR-gamma
(Homo sapiens (Human)) | BDBM329645
((S)-7-ethyl-N¿((R)-1-(4-(ethylsulfonyl)phenyl)-2-m...)Show SMILES CC[C@@H]1N(C[C@H]2CC[C@@H](CC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](COC)c1ccc(cc1)S(=O)(=O)CC |r,wU:25.27,8.11,wD:2.1,5.4,(-5.94,-18.02,;-4.43,-17.7,;-3.95,-16.24,;-4.86,-14.99,;-6.4,-14.99,;-7.17,-13.66,;-6.4,-12.33,;-7.17,-10.99,;-8.71,-10.99,;-9.48,-12.33,;-8.71,-13.66,;-9.48,-9.66,;-8.71,-8.32,;-11.02,-9.66,;-10.25,-8.32,;-3.95,-13.75,;-2.49,-14.22,;-1.16,-13.45,;.18,-14.22,;.18,-15.76,;-1.16,-16.53,;-2.49,-15.76,;1.51,-13.45,;1.51,-11.91,;2.85,-14.22,;4.18,-13.45,;4.18,-11.91,;5.51,-11.14,;5.51,-9.6,;5.51,-14.22,;5.51,-15.76,;6.85,-16.53,;7.91,-15.61,;8.18,-14.22,;6.85,-13.45,;9.11,-16.3,;8.42,-17.5,;9.8,-15.1,;10.3,-16.99,;11.5,-16.3,)| Show InChI InChI=1S/C29H38F3N3O4S/c1-4-26-27-22(17-35(26)16-19-6-10-23(11-7-19)29(30,31)32)14-21(15-33-27)28(36)34-25(18-39-3)20-8-12-24(13-9-20)40(37,38)5-2/h8-9,12-15,19,23,25-26H,4-7,10-11,16-18H2,1-3H3,(H,34,36)/t19-,23-,25-,26-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharmaceuticals, Inc.
US Patent
| Assay Description
Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li... |
US Patent US9663515 (2017)
BindingDB Entry DOI: 10.7270/Q21N837W |
More data for this
Ligand-Target Pair | |
Search and Browse
